P158-02 Experimental Paracoccides brasiliensis infection
increases apoptotic rate in thymus
Souto PCS, Brito VN, Gameiro J, Ricci LC, Cruz-Höfling MA, Verinaud
Many works have shown that immunosuppressive effects induced by systemic
mycosis can be related with damage in primary lymphoid organs. Previous
studies in our laboratory showed that Paracoccidioides brasiliensis
was able to invade the thymus, inducing a severe atrophy. In this study,
we evaluated the relationship between apoptosis and thymic alterations
caused by P. brasiliensis in experimentally infected BALB/c mice. A
large number of cells showing nuclear condensation and karyorrhectic
changes was observed. By TUNEL technique, it was noticed an increase
of apoptotic index during early stages of the infection. We believe
that this argument could be involved in the immunosuppressive phenomenon
frequently observed during the paracoccidioidomycotic infection in humans
and experimental models.
Annual Review of Biomedical Sciences 4: 141-145, 2002 (= A024-02)
P159-02 Inmunodiagnostico de las infecciones por Strongyloides
stercoralis en Chile utilizando la prueba de Elisa
Mercado R, Jercic MI, Torres P, Alcayaga , Costa-Cruz JM, Paula FM,
En presente estudio se efetuó la estandarización de una
prueba ELISA para el diagnóstico de la strongyloidiais humana.
Esta herramienta permitirá contribuir al estudio de casos clínicos
de la parasitosis así como la determinación de la situación
epidemiológica da la infección en Chile.
Revista Médica de Chile 130: 1358-1364, 2002. IF = 0.292
P160-02 Cytotoxicity of derivatives from dehydrocrotonin
on rat cultured hepatocytes
Melo PS, Durán N, Háun M*
Human & Experimental Toxicology 21: 281-288, 2002. IF = 0.954
P161-02 Cytopathology of callus cells infected with
grapevine leafroll-associated virus 3
Scagliusi SMM, Vega J*, Kuniyuki H
Fitopatologia Brasileira 27: 384-388, 2002.
P162-02 The use of molecular beacons combined with
NASBA for the sensitive detection of Sugarcane yellow leaf virus
Gonçalves MC, Klerks MM, Verbeek M, Vega J*, Van Den Heuvel JFJM
European Journal of Plant Pathology 108: 401-407, 2002. IF = 1.475
P163-02 Extraction of caffeine, theobromine and cocoa
butter from Brazilian cocoa beans using supercritical CO2 and ethane
Mohamed RS, Saldaña MDA, Mazzafera P*, Zetzl C, Brunner G
Industrial & Engineering Chemistry Research 41: 6751-6758, 2002.
IF = 1.247
P164-02 Metabolic changes in soybean plants in response
to waterlogging in the presence of nitrate
Sousa CAF, Sodek L*
Changes in N and C compounds in the root system of soybean after flooding
in the presence of nitrate were investigated. Large increases in protein
and amino acids (especially alanine) were recorded. It was concluded
that phloem transport was the source of C for these increases while
nitrate (both exogenous and endogenous) was the source of N.
Physiology and Molecular Biology of Plants 8: 97-104, 2002.
P165-02 The metabolic response of plants to oxygen
Sousa CAF, Sodek L*
A review of metabolic changes underlying the response of plants to oxygen
deficiency (p.ex. on flooding) with special emphasis on N metabolism.
Brazilian Journal of Plant Physiology 14: 83-94, 2002.
P166-02 Do fecal shields provide physical protection
to larvae of the tortoise beetles Plagiometriona flavescens and Stolas
chalybea against natural enemies?
Nogueira-de-Sá F, Trigo JR*
Entomologia experimentalis et applicata 104: 203-206, 2002. IF = 0.915
P167-02 Structure-activity relationships of pyrrolizidine,
alkaloids in insect chemical defense against the orb-weaving spider
Silva KL, Trigo JR*
Journal of Chemical Ecology 28: 657-668, 2002. IF = 1.392
AN008-02 Characterization of monoclonal antibodies
to identify the severe strain of “Capão Bonito” CTV
Stach-Machado, DR*, Peroni LA, Dias LCF, Caporino MC, Muller GW, Targon
MLPN, Machado MA
In: Proceeding of the 15th Conference of the International Organization
of Citrus Virology 165-171, 2002.
C021-02 The Biodiversity Virtual Institute: a Brazilian
experience that can be used as model for research programs on conservation
and sustainable use of the biodiversity
Speglich E, Joly CA*
Despite increasing awareness of its importance, information on biodiversity
is not easily available. Too often, information is dispersed, fragmented,
difficult to access, not integrated with other information, out-of-date,
and underused. To help overcome such problems, in 1999 the Research
Programme in Conservation and Sustainable Use of Biodiversity of the
state of São Paulo, Brazil (BIOTA/FAPESP) and the Virtual Biodiversity
Programme (www.biota.org.br) were established. The programmes are based
on the premises contained in the Convention on Biodiversity. The primary
objective of these programmes is to study biodiversity of the state
of São Paulo. Objectives focus on: understanding the processes
that generate and maintain biodiversity; understanding the processes
that threaten biodiversity; standardizing ways to gather and make information
available to the public, policymakers and decisionmakers; ensuring easy
public access to this information; and improving teaching standards
on conservation of biodiversity and sustainable use. All projects are
linked through the environmental information system of the BIOTA/FAPESP.
This system, in turn, is linked to a 1:50 000 electronic map of the
state of São Paulo. These systems, which are freely available
on the internet, are being used by state branches in charge of biodiversity
protection and social and economic planning. Finally, the BIOTA/FAPESP
has also launched an electronic peer-reviewed journal, BIOTA NEOTROPICA,
to publish research on conservation and sustainable use of biodiversity
in the neotropics (www.biotaneotropica.org.br).
In: Promoting Best Practices for Conservation and Sustainable Use of
Biodiversity of Global Significance in Arid and Semiarid Zones in the
Developing World. Third World Network of Scientific Organizations (TWNSO)
& United Nations Environment Programme (UNEP) & Global Environment
Facility (GEF). BIOTA/FAPESP, 2002.